Neck Growth
You have a tumor or lump on your neck with a diameter of (IE) inches. This causes difficulty breathing and swallowing, causing a −(IE) on all Constitution checks involving physical endurance.
Real-world Examples
Tumor, Goiter, Cyst, Hodgkin’s disease
Assistive Options
No mundane assistance helps with this, and surgery to remove the lump, because of the vital blood vessels in the neck, requires a successful DC 20 + (IE) Wisdom (Medicine) check, failure resulting in death.
Magical Assistance
A Minor Illusion spell can temporarily hide the visibility of the lump but not its physical effects.